Miracle Cure
The Creation of Antibiotics and the Birth of Modern Medicine
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Miracle Cure
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Narrado por:
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Rob Shapiro
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De:
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William Rosen
Sobre este áudio
For fans of Microbe Hunters: the epic history of how antibiotics were born, saving millions of lives and creating a vast new industry known as Big Pharma.
As late as the 1930s, virtually no drug intended for sickness did any good; doctors could set bones, deliver babies, and offer palliative care. That all changed in less than a generation with the discovery and development of a new category of medicine known as antibiotics. By 1955 the age-old evolutionary relationship between humans and microbes had been transformed, trivializing once-deadly infections.
William Rosen captures this revolution with all its false starts, lucky surprises, and eccentric characters. He explains why, given the complex nature of bacteria - and their ability to rapidly evolve into new forms - the only way to locate and test potential antibiotic strains is by large-scale, systematic trial-and-error experimentation. Organizing that research needs large, well-funded organizations and businesses, and so our entire scientific-industrial complex, built around the pharmaceutical company, was born.
Timely, engrossing, and eye opening, Miracle Cure is a must-listen science narrative - a drama of enormous range, combining science, technology, politics, and economics to illuminate the reasons behind one of the most dramatic changes in humanity's relationship with nature since the invention of agriculture 10,000 years ago.
©2017 William Rosen (P)2017 Penguin AudioResumo da Crítica
“Rosen’s highly informed retelling captures the drama of scientists’ quest, against long odds, to find and produce bacteria-killing drugs - and the egos, ambitions, brilliance and resolve that drove them.... It is a strength of “Miracle Cure” that Rosen places its many tales of discovery in their larger contexts...an important contribution to a still-germane yet fast-receding history. And it’s all the more impressive that Rosen, formerly a book editor and publisher, wrote it as he was battling his own intractable disease.” (The Wall Street Journal)
“In Miracle Cure, William Rosen tells the lavish story of antibiotics with the flair and skill of a seasoned novelist, portraying his characters as all too-human, the research often fallible but occasionally transcendent.... Rosen's chronological approach gives the narrative its fluency; his wit and vivid detail make Miracle Cure an absorbing read.... A triumph of science writing that deserves a broad popular audience.” (Minneapolis Star Tribune)
"In this assured chronicle of the 20th-century antibiotics revolution, William Rosen delivers reams of science at a thrilleresque pace. The experimentalists - Gerhard Domagk and Howard Florey among them - are vividly portrayed, as are the patients cured, the pharmaceutical corporations created and the moment in 1943 when bacteriologist Mary Hunt found the ancestor of all penicillin used today, on a mouldy melon. Antibiotic resistance and putative solutions are given their due, including Michael Fischbach's work on microbial-gene clusters in the human microbiome." (Nature)